Identification of a cytisine-based eed-ezh2 protein-protein interaction inhibitor preventing metastasis in triple-negative breast cancer cells

HIGHLIGHTS

• who: Acta et al. from the Key Laboratory of Quality Research Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao, China have published the paper: Identification of a cytisine-based EED-EZH2 protein-protein interaction inhibitor preventing metastasis in triple-negative breast cancer cells, in the Journal: (JOURNAL)
• what: This study shows that targeting EMT and CSC signatures underlying the EED-EZH2 pathway may be a promising therapy for overcoming TNBC metastasis. procedure and high-throughput molecular docking were performed as described in previous reports . In this study, a potent EED-EZH2 . . .
  

   

  

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