Identification of a hypomorphic fancg variant in bernese mountain dogs

HIGHLIGHTS

  • who: Katheryn Meek and colleagues from the University, East Lansing, MI, USA have published the research work: Identification of a Hypomorphic FANCG Variant in Bernese Mountain Dogs, in the Journal: Genes 2022, 13, 1693. of 14/07/2022
  • what: The authors report the presence of coding polymorphism in the gene encoding FANCG near the MTAP/CDKN2A locus. The authors show this canine FANCG variant and previously defined hypomorphic FANCG allele in humans impart similar defects in DNA repair. The authors report the identification of a polymorphism in canine FANCG (Fanconi`s Anemia Complementation Group G . . .

     

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