Identification of a non-canonical g3bp-binding sequence in a mayaro virus nsp3 hypervariable domain

HIGHLIGHTS

• who: Aymeric Neyret from the University of Chile, Chile University of Richmond, United States have published the Article: Identification of a non-canonical G3BP-binding sequence in a Mayaro virus nsP3 hypervariable domain, in the Journal: (JOURNAL)
• what: The authors report that, while lacking FGxF duplication, MAYV depends on G3BPs for replication in mammalian cells. The authors demonstrate that MAYV nsP3 indeed binds G3BPs. The authors report that MAYV has evolved an FGAP sequence in nsP3 HVD to assist its single FGDF motif for G3BPs binding.

SUMMARY

This function was mapped . . .

 



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