Identification of a novel class of anti-melanogenic compounds, (z)-5-(substituted benzylidene)-3-phenyl-2-thioxothiazolidin-4-one derivatives, and their reactive oxygen species scavenging activities

HIGHLIGHTS

• who: Yeongmu Jeong and colleagues from the Laboratory of Medicinal Chemistry, Department of Manufacturing Pharmacy, College of Pharmacy, Department of Pharmacy, College of Pharmacy, Pusan National University, Busan, Korea have published the article: Identification of a Novel Class of Anti-Melanogenic Compounds, (Z)-5-(Substituted benzylidene)-3-phenyl-2-thioxothiazolidin-4-one Derivatives, and Their Reactive Oxygen Species Scavenging Activities, in the Journal: Antioxidants 2022, 11, 948. of /2022/
• how: Kinetic study results indicated that these four analogs inhibited mushroom tyrosinase competitively and this was supported by docking simulation. The authors examined the inhibitory effects . . .
  

   

  

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