Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein

HIGHLIGHTS

• who: Anna Navis from the Department of Pathology, Radboud University Medical Center, , HB Nijmegen, The Netherlands have published the article: Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein, in the Journal: (JOURNAL)
• what: The authors show that this mutation occurs in 6 % of glioblastomas and, like the EGFR mutation EGFRvIII , is relatively specific for this tumor type.
• future: In this respect it will be important in future studies to assess the occurrence of the Δ7-8 mutation in paired samples of primary and recurrent . . .
  

   

  

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