Identification of a novel p53 modulator endowed with antitumoural and antibacterial activity through a scaffold repurposing approach

HIGHLIGHTS

• who: Elisa Nuti and collaborators from the Department of Pharmacy, University of Pisa, Pisa, Italy have published the paper: Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach, in the Journal: Pharmaceuticals 2022, 15, x FOR PEER REVIEW of /2022/
• what: The authors report the identification of a novel MDM2 inhibitor with potential and activity able to reactivate p53.
• how: The most promising compounds were tested in_vitro to confirm whether they showed a detectable inhibition of MDM2. This result is in accordance with the increase . . .
  

   

  

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