HIGHLIGHTS
- who: Angewandte and collaborators from the (UNIVERSITY) have published the Article: Identification of a Novel Pseudou2010Natural Product Type IV IDO1 Inhibitor Chemotype, in the Journal: (JOURNAL)
SUMMARY
The novel inhibitor class, termed apoxidoles, has a distinct chemotype and induces unprecedented structural changes not observed for other type IV inhibitors, as revealed by a crystal_structure analysis.[12] Angew. Kyn levels can be reduced by small_molecules that e_g inhibit IDO1 directly,[24] redox-cycling compounds,[25] decrease IDO1 expression, e_g via inferring with JAK/STAT signalling,[26] inactivate IDO1 via post-translational modification or prevent . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.