Identification of an inhibitory domain in gtpase-activating protein p190rhogap responsible for masking its functional gap domain

HIGHLIGHTS

  • who: Capucine Hu00e9raud from the The pKH3-p, WT containing the rat full-length p RhoGAP (GenBank under accession noM94721) was a generous gift from I. Macara (Vanderbilt University). The two have published the article: Identification of an inhibitory domain in GTPase-activating protein p190RhoGAP responsible for masking its functional GAP domain, in the Journal: (JOURNAL) of January/25,/2022
  • how: To evaluate the involvement of the PLS in the regulation of p190A GAP activity the authors analyzed F-actin organization as a read-out of Rho GTPase activity. The same results were obtained when . . .

     

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