Identification of arhgef12 and prkci as genetic modifiers of retinal dysplasia in the crb1rd8 mouse model

HIGHLIGHTS

  • who: Sonia M. Weatherly and collaborators from the Immunology, Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, University, Bangkok, Thailand have published the research: Identification of Arhgef12 and Prkci as genetic modifiers of retinal dysplasia in the Crb1rd8 mouse model, in the Journal: (JOURNAL) of March/12,/2022
  • what: In this study two modifiers of a gene associated with retinal damage leading to childhood blindness in humans (CRB1) were identified in mice. The study has highlighted the utility of a sensitized mutagenesis screen to identify Crb1rd8 modifier genes, which will continue to . . .

     

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