HIGHLIGHTS
- who: Samia Nisar et al. from the address:, Pakistan have published the research work: Identification of ATP2B4 Regulatory Element Containing Functional Genetic Variants Associated with Severe Malaria, in the Journal: (JOURNAL)
- what: The authors aimed to identify potential causal variants located in these loci and demonstrate their activity. The authors provide evidence that several SNPs were associated with SM in a Senegalese population, alter the activity of an Epromoter affecting the expression of ATP2B4 and modulate intracellular calcium concentration. The authors focused the analysis on the SNPs for which significant GWAS signals have been replicated . . .
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