Identification of bone metastatic and prognostic alternative splicing signatures in prostate adenocarcinoma

HIGHLIGHTS

  • who: Jiwen Zhu from the (UNIVERSITY) have published the Article: Identification of Bone Metastatic and Prognostic Alternative Splicing Signatures in Prostate Adenocarcinoma, in the Journal: (JOURNAL)
  • what: In the study, 390 splicing factors were retrieved from the SpliceAid2 database (Piva et_al 2009). The results of the study demonstrated that aberrant ASE of PIP5K1C was significantly related to poor prognosis and tumor metastasis in PRAD patients.
  • how: The ASEs in pooled mRNA samples from 500 PRAD cases collected in the TCGA dataset were analyzed.
  • future: Though all the results were confirmed by . . .

     

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