Identification of cell wall synthesis inhibitors active against mycobacterium tuberculosis by competitive activity-based protein profiling

HIGHLIGHTS

• who: Michael Li from the Brook University, Stony Brook, NY, USA have published the research: Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling, in the Journal: (JOURNAL) of May/19,/2022
• what: After screening 200 compounds the authors focus on 4 compounds form structure-activity series. In contrast with the study , the targets of other SH inhibitors, such as THL, lalistat, EZ120, and CyC17, were identified without comparison with the targets of a related inactive compound (Lehmann et_al, 2016, 2018; Nguyen et_al, 2017; Ravindran et_al, 2014). The . . .
  

   

  

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