Identification of compounds with activity against trypanosoma cruzi within a collection of synthetic nucleoside analogs

HIGHLIGHTS

• who: Berta Barnadas-Carceller and collaborators from the Federal University of Su00e3o Paulo, Brazil have published the paper: Identification of compounds with activity against Trypanosoma cruzi within a collection of synthetic nucleoside analogs, in the Journal: (JOURNAL)
• what: The authors focused on evaluating the interactions of prioritized compounds with enzymes TcADSL, TcAK, TcAPRT, Frontiers in Cellular and Infection Microbiology 100 1+XHillSlope IC50HIllSlope Compounds with an IC50 >10u00d7 that of BNZ were considered inactive against T. cruzi.
• how: The authors evaluated the anti-parasitic activity of 23 purine analogs with different substitutions in . . .
  

   

  

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