Identification of darunavir derivatives for inhibition of sars-cov-2 3clpro

HIGHLIGHTS

  • who: Ling Ma and collaborators from the Institute of Medicinal Biotechnology, Chinese Academy of Medical Science, Beijing, China have published the paper: Identification of Darunavir Derivatives for Inhibition of SARS-CoV-2 3CLpro, in the Journal: (JOURNAL) of 23/09/2022
  • how: The results showed that all the Z factors (0.84) %CV (13%) and S/N(22.3) met the criteria required for the high-throughput screening (HTS) assay . The result showed that both the compounds exhibited a very limited inhibitory effect providing evidence to support the specific_activity of 29# and 50# against the . . .

     

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