Identification of daxx as a restriction factor of sars-cov-2 through a crispr/cas9 screen

HIGHLIGHTS

  • who: Alice Mac Kain from the Universitu00e9 UMR, Virus and Immunity, Paris, FranceUniversity of have published the article: Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors performed a CRISPR/Cas9 screen designed to identify restriction factors for SARS-CoV-2, assessing the ability of 1905 ISGs to modulate SARS-CoV-2 replication in human epithelial lung cells. The authors report that the Death domain-associated protein 6 (DAXX), a scaffold protein residing in PML nuclear bodies30 and . . .

     

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