Identification of druggable inhibitory immune checkpoints on natural killer cells in covid-19

HIGHLIGHTS

  • who: Olivier Demaria from the CNRS Hôpital de la Timone, Immunology, Marseille Immunopole, Marseille, France have published the research work: Identification of druggable inhibitory immune checkpoints on Natural Killer cells in COVID-19, in the Journal: (JOURNAL) of 15/06/2020

SUMMARY

    Received Published Cellular and amp; Molecular Immunology 17:995 - 997 incubation with monalizumab an anti-NKG2A mAb blocking the inhibitory interaction with HLA-E, was able to unleash their killing ability (Fig 1g). These data suggest that therapeutic interventions may improve NK cell functions, facilitating virus elimination, and support the . . .

     

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