Identification of essential filovirion-associated host factors by serial proteomic analysis and rnai screen*

HIGHLIGHTS

  • who: Kevin B. Spurgers from the Inc have published the article: Identification of Essential Filovirion-associated Host Factors by Serial Proteomic Analysis and RNAi Screen*, in the Journal: (JOURNAL) of July/19,/2010
  • what: The authors report here LC-MS/MS analysis of protein lysates from highly purified ebolavirus and marburgvirus virions.
  • future: The use of primary human cells in future studies should mitigate unnec- Molecular and amp Cellular Proteomics 9.12 essary complications in the host target and drug discovery efforts. Ongoing and future experiments will attempt to answer whether or not . . .

     

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