HIGHLIGHTS
- who: Elisha H. McCrory and colleagues from the MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, Scotland, UK. have published the research work: Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to, in the Journal: (JOURNAL) of 17/Nov/2022
- what: Interestingly, Ser136 of IRAK2, one of the sites of ubiquitylation identified in this study, has been reported to undergo phosphorylation when mouse BMDM are stimulated with lipopolysaccharide, an activator of TLR4 .
- how: The results indicated that the formation of hydroxylamine . . .
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