Identification of fibroblast growth factor receptor 3 (fgfr3) as a protein receptor for botulinum neurotoxin serotype a (bont/a)

HIGHLIGHTS

  • who: Serotype A (BoNT/A and colleagues from the Editor: Steven RBlanke, University of Illinois, United States of America have published the article: Identification of Fibroblast Growth Factor Receptor 3 (FGFR3) as a Protein Receptor for Botulinum Neurotoxin Serotype A (BoNT/A), in the Journal: (JOURNAL) of May/16,/2013
  • what: The studies presented in this manuscript identify FGFR3 expressed in motor neurons at MNTs as a functional protein receptor for BoNT/A. The authors show that BoNT/A binds to FGFR3 with high affinity and functions as an agonist ligand for FGFR3. Since ligand . . .

     

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