HIGHLIGHTS
- who: Lipei Shao from the (UNIVERSITY) have published the research: Identification of genomic determinants contributing to cytokine release in immunotherapies and human diseases, in the Journal: (JOURNAL)
- what: The study explored the genomic determinants which trigger cytokine release in immunotherapy and several other diseases. Given the apparent role of PFKFB4 in cytokine release, further studies aimed at developing effective drugs target on PFKFB4 and glycolysis appear particularly promising.
- how: Concerning glycolytic pathway activity the results showed that pathway activity also increased during SARS-CoV-2 infection and COVID-19 development (Fig 3D-F . . .
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