Identification of hmga2 as a predictive biomarker of response to bintrafusp alfa in a phase 1 trial in patients with advanced triple-negative breast cancer

HIGHLIGHTS

  • who: Alexander Spira from the Yonsei University Health System, China have published the research work: Identification of HMGA2 as a predictive biomarker of response to bintrafusp alfa in a phase 1 trial in patients with advanced triple-negative breast cancer, in the Journal: (JOURNAL) of May/15,/2020
  • what: The authors report results from the global phase 1 study NCT02517398 evaluating bintrafusp alfa in an expansion cohort of patients with pretreated, advanced TNBC, including the results of an extensive, integrated tumor biomarker evaluation. In this manuscript, the authors report that expression of HMGA2 in tumor . . .

     

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