Identification of host transcriptional networks showing concentration-dependent regulation by hpv16 e6 and e7 proteins in basal cervical squamous epithelial cells

HIGHLIGHTS

  • who: Stephen P. Smith from the Cambridge University have published the research: Identification of host transcriptional networks showing concentration-dependent regulation by HPV16 E6 and E7 proteins in basal cervical squamous epithelial cells, in the Journal: Scientific Reports Scientific Reports
  • how: Microarray data were analysed using the R statistical programming language32. For negative controls the authors used untreated cells plus those transfected with pooled non-targeting control siRNAs (ON-TARGET plus non-targeting D-001810 Dharmacon) again at 40 nM.

SUMMARY

    Such events are associated with phenotypic progression of the epithelia . . .

     

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