HIGHLIGHTS
- who: Guillermo Carbajosa from the (UNIVERSITY) have published the research: Identification of human mitochondrial RNA cleavage sites and candidate RNA processing factors, in the Journal: (JOURNAL)
- what: The authors develop a method to detect and quantify mitochondrial cleavage events from standard sequencing data and apply this approach to human whole blood data from > 1000 samples across independent cohorts. Within this study, it was shown that technical features of Nanopore direct RNA sequencing led to truncation events in mitochondrial transcripts 10-15bp from the 5u2032 end of genes, and as such, the authors removed putative cleavage . . .
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