Identification of immune microenvironment subtypes and signature genes for alzheimer’s disease diagnosis and risk prediction based on explainable machine learning

HIGHLIGHTS

• who: Yongxing Lai from the Huazhong University of Science and Technology, China have published the Article: Identification of immune microenvironment subtypes and signature genes for Alzheimeru2019s disease diagnosis and risk prediction based on explainable machine learning, in the Journal: (JOURNAL)
• what: The authors conducted the LASSO regression model to determine the optimal variables from immune cells. Global and local explanations of the machine_learning models To explain how the machine_learning model worked in predicting AD onset, the authors aimed to open the u2018black box` in the XGBoost and LightGBM models via SHAP values and elucidate the . . .
  

   

  

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