Identification of naprt inhibitors with anti-cancer properties by in silico drug discovery

HIGHLIGHTS

• who: Moustafa S. Ghanem and colleagues from the Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy have published the article: Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery, in the Journal: Pharmaceuticals 2022, 848 of /2022/
• what: The authors report on the identification of two additional chemical entities that function as NAPRT inhibitors with antineoplastic activity comparable to 2-HNA and with desirable drug-like features. These differences between the studies and the work by Chowdhry and coworkers could be explained by the different cell lines . . .
  

   

  

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