Identification of novel arachidonic acid 15-lipoxygenase inhibitors based on the bayesian classifier model and computer-aided high-throughput virtual screening

HIGHLIGHTS

• who: Yinglin Liao and collaborators from the The First Clinical College, Guangdong Medical University, Zhanjiang, China have published the Article: Identification of Novel Arachidonic Acid 15-Lipoxygenase Inhibitors Based on the Bayesian Classifier Model and Computer-Aided High-Throughput Virtual Screening, in the Journal: Pharmaceuticals 2022, 1440 of 13/08/2022
• what: In this study, a coherent computer-aided screening process was designed to obtain compounds with ALOX15 inhibitory potential from a database of purchasable compounds. Various fingerprint- descriptor combinations were attempted during the model construction, whereas the area under the ROC curve (AUC) values . . .
  

   

  

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