Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel

HIGHLIGHTS

• who: Evgeny G. Chulkov et al. from the Florida, United States of America, Department of Pharmacology, University of Minnesota Medical School have published the research work: Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel, in the Journal: (JOURNAL) of June/17,/2021
• what: The authors report successful miniaturization of a reporter assay (6μl assay volume) to monitor the activity of a parasitic flatworm ion_channel, Sm.TRPMPZQ. This approach will enable further HTS campaigns to provide insight about the properties and regulation of this recently discovered flatworm ion_channel that . . .
  

   

  

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