Identification of potential druggable targets and structure-based virtual screening for drug-like molecules against the shrimp pathogen enterocytozoon hepatopenaei

HIGHLIGHTS

  • who: Prasenjit Paria and Anchalee Tassanakajon from the Faculty of Science, Chulalongkorn University, Bangkok, Thailand have published the Article: Identification of Potential Druggable Targets and Structure-Based Virtual Screening for Drug-like Molecules against the Shrimp Pathogen Enterocytozoon hepatopenaei, in the Journal: (JOURNAL)
  • what: In this study five potential druggable targets of EHP namely aquaporin (AQP) cytidine triphosphate (CTP) synthase thymidine kinase (TK) methionine aminopeptidase2 (MetAP2) and dihydrofolate reductase (DHFR) were identified via functional classification of the whole EHP proteome. This study aimed to identify novel compounds with high binding affinities and high chemical complementarities . . .

     

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