Identification of prognostic stemness biomarkers in colon adenocarcinoma drug resistance

HIGHLIGHTS

  • who: Ziyue Li from the University, Guangzhou, China have published the research: Identification of prognostic stemness biomarkers in colon adenocarcinoma drug resistance, in the Journal: (JOURNAL)
  • how: To elucidate the underlying interconnected systems the authors examined relationships between the levels of TFs PSRGs and 50 cancer hallmarks by a Pearson correlation analysis. As the authors combined the univariate Cox regression analysis 18 DEGs PRSGs and genes with prognostic values (Fig 7A B) the authors identified and incorporated this information into the Elastic Net regression analysis (model parameters u03b1=0.0417 u03b2=1.7022). Showed that . . .

     

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