Identification of prolactin receptor variants with diverse effects on receptor signalling (79 characters, 85 characters allowed) caroline m. gorvin , paul j. newey , rajesh v. thakker

HIGHLIGHTS

  • who: Prolactinoma and colleagues from the Department of Medicine, University of Oxford, Oxford, LJ, UK have published the research: Identification of prolactin receptor variants with diverse effects on receptor signalling (79 characters, 85 characters allowed) Caroline M. Gorvin , Paul J. Newey , Rajesh V. Thakker, in the Journal: (JOURNAL)
  • how: To assess the effects of the PRLR variants on Akt signalling the authors investigated PRL-induced responses of phospho-Akt by AlphaScreen analysis and luciferase reporter activity by the Akt-target gene FOXO1 (Essaghir et_al 2009).
  • future: Src family kinases and MAPK signalling proteins . . .

     

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