Identification of rev-erbα as a physiological repressor of apoc-iii gene transcription1

HIGHLIGHTS

• who: Eric Raspé from the Centre II, Lille, France have published the research work: Identification of Rev-erbα as a physiological repressor of apoC-III gene transcription1, in the Journal: (JOURNAL) of 27/09/2002
• what: The authors report here an increase in serum and liver mRNA levels of apoC-III that accompanied elevated triglycerides in male Rev-erb -deficient mice. The authors identified Rev-erb as a dominant repressor of apoC-III promoter activity.
• how: Similar results were obtained with hROR 1 (data not shown).
• future: Studies are required to . . .
  

   

  

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