Identification of the ataxin-1 interaction network and its impact on spinocerebellar ataxia type 1

HIGHLIGHTS

  • who: Jiu-Ming Chen from the (UNIVERSITY) have published the research work: Identification of the ataxin-1 interaction network and its impact on spinocerebellar ataxia type 1, in the Journal: (JOURNAL)
  • what: The study demonstrates the phosphorylation of ataxin-1 may involve in the pathogenesis of SCA1.
  • how: These data indicated that the polyglutamine expansion in ataxin-1 had little effect on the ability of ataxin-1 to bind target RNAs.
  • future: More studies are needed to explore the ataxin-1 function.

SUMMARY

    Two ataxin-1 binding . . .

     

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