HIGHLIGHTS
SUMMARY
Based on the cell cycle scores and cell cycle-related gene_expression, the authors separated patients with NSCLC into three distinct types and evaluated their association with prognosis, metabolic reprogramming, immune microenvironments, and cell death pathways. The major cause of tumorigenesis is the unrestricted cell proliferation after the cell cycle disorder and therefore, the tumor could be regarded as a cell cycle disease. Red represents a dangerous gene, indicating that the greater the level of gene_expression, the worse the prognosis of patients; blue shows a protective gene indicating that the higher the level of gene_expression . . .
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