Identification of the osteoarthritis signature gene pdk1 by machine learning and its regulatory mechanisms on chondrocyte autophagy and apoptosis

HIGHLIGHTS

  • who: Jinzhi Meng et al. from the University of Pisa, Italy have published the article: Identification of the osteoarthritis signature gene PDK1 by machine learning and its regulatory mechanisms on chondrocyte autophagy and apoptosis, in the Journal: (JOURNAL)
  • what: The authors systematically and comprehensively screened for the first-time disease signature genes for OA based on publicly available databases and conducted a series of in_vitro cell experiments for validation and exploration.
  • how: Similarly the authors conducted GO functional enrichment analysis to explore the biological frontiersin.org 10.3389/fimmu.2022.1072526 functions of . . .

     

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