HIGHLIGHTS
- who: Tan Zhang from the Universitu00e9de Sherbrooke, Canada University of Michigan, United States have published the article: Identifying u03b1-KG-dependent prognostic signature for lower-grade glioma based on transcriptome profiles, in the Journal: (JOURNAL)
- what: The authors aimed to explore the transcriptomic alterations and prognostic value of a-KGdependent dioxygenases between IDHWT and IDHMUT LGG samples. The results revealed that the enzyme-based risk signature was shown to have prognostic significance for IDH mutant LGG; thereby, the authors propose that the signature is a useful supplement for the development of IDHMUT individual management.
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