Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe copd

HIGHLIGHTS

  • who: Alen Faiz from the DepartmentUniversity of have published the research work: Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD, in the Journal: Scientific Reports Scientific Reports
  • what: The study was originally designed to compare the effect of beclomethasone/formoterol (BDP/F) to budesonide/formoterol (BUD/F) treatment in patients with severe COPD and hyperinflation.
  • how: Data was analyzed using limma comparing COPD patients (GOLD stage II and III) to healthy controls in small airway brushings. Genes were ranked according to the generated t-statistic from . . .

     

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