Identifying and exploring the candidate susceptibility genes of cirrhosis using the multi-tissue transcriptome-wide association study

HIGHLIGHTS

  • who: Transcriptome-Wide Association and colleagues from the Shandong University, China have published the Article: Identifying and Exploring the Candidate Susceptibility Genes of Cirrhosis Using the Multi-Tissue Transcriptome-Wide Association Study, in the Journal: (JOURNAL)
  • what: The authors employed TWAS to explore the cirrhosisrelated genes. The authors used tissue-specific TWAS to explore the association of genetically predicted gene_expression with cirrhosis in European ancestry and identified 10 genes in four tissues as potential cirrhosis-related genes, including two in the liver (SKIV2L and JPH4), three in the pancreas (UQCC2, RP1191I8.3, and MAU2), two . . .

     

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