HIGHLIGHTS
- who: Ling Deng from the Antibodies Antibodies used in this study are as follow: CDC7, MCM2, PARP, Caspase3, cleaved-Caspase3, Bcl-2, Bax, Cyclin, Cyclin, and GAPDH were purchased from Proteintech Group, UK have published the research: Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening, in the Journal: (JOURNAL)
- what: Based on the screening data and the fact that cell cycle inhibitors were hits for SCLC therapy, the authors focused on the role of CDC7 in chemo-resistant SCLC.
- how: These data indicated . . .
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