Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis

HIGHLIGHTS

  • who: Max Kaufmann from the the University have published the research: Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis, in the Journal: (JOURNAL) of March/12,/2021
  • what: The authors investigate whether the therapeutic resistance of progressive MS can be attributed to chronic immune cell accumulation behind the blood-brain barrier (BBB). The authors provide evidence that a population of CNS-homing CD4+ T_cells (T09) that is relevant to the pathophysiology of RRMS is also detected in the CNS of patients with progressive disease. Limitations of study This . . .

     

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