HIGHLIGHTS
- who: Kimberly Luttik and colleagues from the Interdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA have published the research: Identifying Disease Signatures in the Spinocerebellar Ataxia Type 1 Mouse Cortex, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of 21/Dec/2021
- what: The authors aimed to understand the functional impact of mutant ataxin-1 expression in extra-cerebellar regions and identify potential molecular mechanisms underlying observed clinical phenotypes, including cognitive impairment.
- how: The authors identified progressive cortical pathology and significant transcriptomic changes in the motor of a . . .
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