Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from gwas summary data

HIGHLIGHTS

• who: Hung Mai from the Perelman School of Medicine, of Pennsylvania, Walk, PA, USA have published the research: Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data, in the Journal: (JOURNAL)
• what: As a result of the analysis the authors identified 10 genes that are highly associated with both TBV and ICV. The authors propose to use S-PrediXcan to integrate the GWAS summary statistics of an imaging trait with PrediXcan models linking SNPs to gene_expression data in a specific brain tissue. The authors aim to identify promising . . .
  

   

  

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