HIGHLIGHTS
- who: Jennifer L. Norcliffe from the minantly rely on two approaches: (i) in vitro target-directed screening using biochemical assays have published the article: Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform, in the Journal: (JOURNAL) of 17/Nov/2017
- what: This approach has been adopted for antiprotozoal drug discovery12,25,26. This work reports the largest yeast-based, target-directed assay undertaken to date against targets from any disease state. This research demonstrated the tractability of yeast-based uHTS to . . .
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