Identifying metabolic shifts in crohn`s disease using `omics-driven contextualized computational metabolic network models

HIGHLIGHTS

  • who: Philip Fernandes from the DepartmentUniversity of of Pediatric Gastroenterology, Emory Children`s Center, Atlanta, GA, USA have published the article: Identifying metabolic shifts in Crohn`s disease using `omics-driven contextualized computational metabolic network models, in the Journal: Scientific Reports Scientific Reports
  • what: Using random forest classification to identify discriminating reactions, the models determined whether a sample was from diseased versus control tissue, achieving 80% accuracy after 100 train-test splits in classifying CD versus control patients. Of note, the model had an average accuracy of 56% in classifying whether transcriptomic data originated from . . .

     

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