Identifying sars-cov-2 variants of concern through saliva-based rt-qpcr by targeting recurrent mutation sites

HIGHLIGHTS

  • who: Rachel E. Ham et al. from the Clemson University, Clemson, South Carolina, USA have published the paper: Identifying SARS-CoV-2 Variants of Concern through Saliva-Based RT-qPCR by Targeting Recurrent Mutation Sites, in the Journal: (JOURNAL) of 22/Dec/2021

SUMMARY

    This prompted researchers to design assays that rely on target gene failure for detection of deletions or single nucleotide polymorphisms (SNPs) in VOCs. RT-qPCR assays featuring competitive probes for both reference and mutation sequences increases specificity, providing a more robust strain-typing panel. Many VOCs contain advantageous genotypes . . .

     

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