Identifying the potential transcriptional regulatory network in hirschsprung disease by integrated analysis of microarray datasets

HIGHLIGHTS

  • who: Wenyao Xu and colleagues from the Department of Pediatric, China have published the research work: Identifying the potential transcriptional regulatory network in Hirschsprung disease by integrated analysis of microarray datasets, in the Journal: (JOURNAL)
  • what: As mentioned previously, the miRNAs identified in this study had AUC values of more than 0.8 and remained unclear so far in HSCR, which provided new cues for future biomarker study of HSCR treatment and diagnosis. The authors constructed a potential TF-miRNA-mRNA network, of which a key module with four functional genes (PIM3, CHUK, F2RL1, and . . .

     

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