Ifn-γ blockade after genetic inhibition of pd-1 aggravates skeletal muscle damage and impairs skeletal muscle regeneration

HIGHLIGHTS

  • who: Shuzhao Zhuang from the University of Sport, China have published the Article: IFN-u03b3 blockade after genetic inhibition of PD-1 aggravates skeletal muscle damage and impairs skeletal muscle regeneration, in the Journal: (JOURNAL)
  • what: Blocking IFN-u03b3 signaling after PD-1 knockout does not alleviate skeletal muscle damage or promote its regeneration.
  • how: Data were analyzed using SPSS 26.0 and presented as mean u00b1 standard deviation. The results showed that PD-1 knockout and IFN-u03b3 blockade promote neutrophil infiltration but the combined effect is not greater than blocking IFN . . .

     

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