Ifn-γ transforms the transcriptomic landscape and triggers myeloid cell hyperresponsiveness to cause lethal lung injury

HIGHLIGHTS

• who: Atul K. Verma from the Fudan University, China have published the paper: IFN-u03b3 transforms the transcriptomic landscape and triggers myeloid cell hyperresponsiveness to cause lethal lung injury, in the Journal: (JOURNAL)
• what: The authors show in this model that antibiotic therapy restores bacterial control but is not sufficient to rescue animals from inflammatory lung damage . The authors demonstrate that IFN-g induces a transcriptional shift in airway immune cells during IAV/ MRSA coinfection. The authors have investigated the signaling pathway underlying IFN-g-driven lethal lung inflammation during IAV/MRSA coinfection. The authors . . .
  

   

  

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