HIGHLIGHTS
- who: Edyta Makuch et al. from the u0141ukasiewicz Research Network-PORT Polish Center for Technology Development, Wrocu0142aw, Poland have published the research work: IFN-Induced CXCL10 Chemokine Expression Is Regulated by Pellino3 Ligase in Monocytes and Macrophages, in the Journal: (JOURNAL)
- what: The authors demonstrate that is important for IFNu03b2-induced phosphorylation and nuclear translocation of STAT1/STAT2/IRF9 complex which interacts with promoter and enhances its expression. The authors characterize a novel molecular mechanism allowing Pellino3-dependent modulation of the IFNu03b2-induced response in BMDM and THP-1 cell lines. The authors show for . . .
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