Ifn- ? -secreting-mesenchymal stem cells exert an antitumor effect in vivo via the trail pathway

HIGHLIGHTS

  • who: Xinyuan Yang and colleagues from the Department of Gynecology and Obstetrics, First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China have published the Article: IFN- 𝛾 -Secreting-Mesenchymal Stem Cells Exert an Antitumor Effect In Vivo via the TRAIL Pathway, in the Journal: (JOURNAL) of 26/05/2014
  • what: The authors show that IFN-𝛾-modified MSCs continuously express TRAIL and induce apoptosis in lung cancer cells by activating caspase-3 within the target cells. Based on the work , the benefits of IFN-𝛾 may be exploited through the genetic engineering of MSCs . . .

     

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