Ige glycans promote anti-ige igg autoantibodies that facilitate ige serum clearance via fc receptors

HIGHLIGHTS

• who: Kevin Plattner from the The University of Texas Health Science Center at San Antonio, United States have published the research: IgE glycans promote anti-IgE IgG autoantibodies that facilitate IgE serum clearance via Fc Receptors, in the Journal: (JOURNAL)
• what: The authors show that booster immunizations can even enhance the anti-IgE IgG response suggesting that repeated exposure to IgE-allergen IC might lead to a beneficial anti-IgE IgG response. The adjuvant effect of IgE for antigens has been previously demonstrated, but here the authors show that glycans are critical for this effect . . .
  

   

  

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